Format

Send to

Choose Destination
Res Microbiol. 2001 Apr-May;152(3-4):271-8.

Polyamine uptake systems in Escherichia coli.

Author information

1
Graduate School of Pharmaceutical Sciences, Chiba University, Japan. iga16077@p.chiba-u.ac.jp

Abstract

The polyamine content of cells is regulated by biosynthesis, degradation, and transport. In Escherichia coli, the genes for three different polyamine transport systems have been cloned and characterized. Two uptake systems (putrescine-specific and spermidine-preferential) are ABC transporters, each consisting of a periplasmic substrate binding protein, two transmembrane proteins, and a membrane-associated ATPase. The third transport system, catalyzed by PotE, mediates both uptake and excretion of putrescine. In this article, the properties of the first two polyamine uptake systems are reviewed in detail.

PMID:
11421274
DOI:
10.1016/s0923-2508(01)01198-6
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center