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Arch Pathol Lab Med. 2001 Jul;125(7):954-7.

Allergic granulomatosis secondary to a limited form of Churg-Strauss syndrome.

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Department of Pathology, University of Cincinnati, Cincinnati, Ohio 45267-0529, USA.


Allergic granulomatosis is a disorder of obscure etiology characterized by infiltration of lymph nodes with histiocytic granulomas and eosinophils. In this report, we describe a case of allergic granulomatosis that is consistent with Churg-Strauss disease limited to lymph nodes. The histologic findings of this patient's lymph nodes demonstrated eosinophilic abscesses and ring-shaped necrotizing and nonnecrotizing granulomas surrounding hyperplastic germinal centers. We report herein a rare type of reactive lymphadenopathy and present its histologic, immunohistochemical, and flow cytometric findings, which may allow its distinction from other lymphadenopathies.

[Indexed for MEDLINE]

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