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Clin Infect Dis. 2001 Jul 15;33(2):210-9. Epub 2001 Jun 14.

Vancomycin-resistant enterococci: mechanisms and clinical observations.

Author information

1
Department of Medicine, Division of Infectious Diseases, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA. hogold@caregroup.harvard.edu

Abstract

Enterococci are not generally regarded as highly virulent bacterial pathogens. However, resistance to many antimicrobial drugs complicates treatment of enterococcal infections. Acquired resistance to high concentrations of glycopeptide antibiotics, specifically vancomycin, has exacerbated this problem. This article seeks to concisely review the mechanisms of that resistance and its effects on clinical management of enterococcal infections, as well as clinical microbiology and infection control.

PMID:
11418881
DOI:
10.1086/321815
[Indexed for MEDLINE]

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