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Eur J Med Res. 2001 May 29;6(5):215-8.

Human natriuretic peptides exhibit antimicrobial activity.

Author information

1
IPF PharmaCeuticals GmbH, Hannover, Germany.

Abstract

Here we describe a novel function for members of the well-characterized human natriuretic peptide family. Human "brain-type natriuretic peptide" (hBNP-32) as well as other members of this peptide class are antimicrobially active against Gram-positive and Gram-negative bacteria and yeast in a dose-dependent manner. This activity of natriuretic peptides is comparable to that of known antimicrobial peptides such as casocidins or magainins.

PMID:
11410403
[Indexed for MEDLINE]

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