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Am J Ophthalmol. 1979 Sep;88(3 Pt 1):432-49.

Vitreoretinal degeneration as a sign of generalized connective tissue diseases.

Abstract

Dominant vitreoretinal degeneration was first described by Wagner as a benign ocular condition. This term has since become widely associated with a familial retinal degenerative process accompanied by retinal detachments, even though nobody in the family described by Wagner suffered from a retinal detachment. Vitreoretinal degeneration, often progressing to detachments, occurs also in several distinct bone dysplasias. I have provided a classification of syndromes with vitreoretinal degeneration and its signficance as a sign of connective tissue diseases (probably involving type II collagen). In this sense, it is similar to ectopia lentis as a sign of various connective tissue diseases.

PMID:
114056
DOI:
10.1016/0002-9394(79)90645-7
[Indexed for MEDLINE]

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