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Life Sci. 2001 Apr 27;68(22-23):2541-7.

Snake toxins that bind specifically to individual subtypes of muscarinic receptors.

Author information

1
Department of Molecular and Cellular Pharmacology, University of Miami School of Medicine, FL 33101, USA. lpotter@miami.edu

Abstract

This paper discusses the properties of the three most specific ligands found for the extracellular faces of M1, M2 and M4 muscarinic receptors (m1-toxin1, m2-toxin and m4-toxin, respectively). The primary goal of this paper is to show the known and potential usefulness of these toxins and their biotinylated, radioactive, fluorescent and mutated derivatives.

PMID:
11392624
DOI:
10.1016/s0024-3205(01)01050-5
[Indexed for MEDLINE]

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