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Nat Rev Mol Cell Biol. 2001 Jun;2(6):467-75.

The hunting of the Src.

Author information

1
Department of Molecular and Cell Biology, University of California, 401 Barker Hall #3204, Berkeley, California 94720-3204, USA. smartin@socrates.berkeley.edu.

Abstract

The non-receptor tyrosine kinase Src is important for many aspects of cell physiology. The viral src gene was the first retroviral oncogene to be identified, and its cellular counterpart was the first proto-oncogene to be discovered in the vertebrate genome. Src has been important, not only as an object of study in itself, but also as an entry point into the molecular genetics of cancer.

PMID:
11389470
DOI:
10.1038/35073094
[Indexed for MEDLINE]

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