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Scand J Clin Lab Invest. 2001 May;61(3):237-46.

Urinary excretion of diazepam metabolites in healthy volunteers and drug users.

Author information

1
National Institute of Forensic Toxicology, Oslo, Norway. Anne.Smith-Kielland@labmed.uio.no

Abstract

Urinary excretion profiles of diazepam metabolites were investigated. The subjects were healthy volunteers receiving one single 10-mg dose of diazepam or drug abusers starting a prison sentence. Urinary excretion of metabolites was analysed by immunological screening, liquid chromatography and gas chromatography-mass spectrometry. Relating the metabolite concentration to creatinine concentration in the specimens decreased sample-to-sample variations. In some cases such correction could protect a subject from erroneous accusations of a new intake.

PMID:
11386610
[Indexed for MEDLINE]

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