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Nutrition. 2001 May;17(5):409-13.

Is insulin an antiinflammatory molecule?

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From EFA Sciences LLC, Norwood, Massachusetts, USA.


I suggest that insulin suppresses the secretion and antagonizes the harmful effects of tumor necrosis factor-alpha, macrophage migration-inhibitory factor, and superoxide anion. Therefore, the glucose-insulin-potassium regimen might be beneficial in acute myocardial infarction and useful in the management of patients with septicemia, septic shock, and other inflammatory diseases in which tumor necrosis factor-alpha and macrophage migration-inhibitory factor have important roles.

[Indexed for MEDLINE]

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