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Curr Opin Neurol. 2001 Jun;14(3):355-9.

Chlamydia pneumoniae infection of the central nervous system.

Author information

1
Multiple Sclerosis Research Center, Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Abstract

Chlamydia pneumoniae is a common respiratory pathogen that is now being implicated in a number of chronic diseases. That the organism can infect vascular endothelium, macrophages and smooth muscle cells suggests that it may play a role in many systemic diseases. The present review focuses on the possibility that the central nervous system can also be a target of this agent. The tropism of C. pneumoniae to the neural tissue suggests it may play a role in diverse neurologic diseases, including Alzheimer's disease, multiple sclerosis and giant-cell arteritis.

PMID:
11371760
[Indexed for MEDLINE]

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