Short report: Hyperammonaemia in critically ill septic infants

Arch Dis Child. 2001 Jun;84(6):512-3. doi: 10.1136/adc.84.6.512.

Abstract

Three infants with subphrenic abscess, pyonephrosis, and obstructive ureterocoele respectively had grossly increased concentrations of plasma ammonia. This was considered to be a result of infections with urea splitting organisms. All died in spite of intensive care support, including specific measures to reduce plasma ammonia.

Publication types

  • Case Reports

MeSH terms

  • Ammonia / metabolism
  • Critical Care
  • Critical Illness
  • Fatal Outcome
  • Female
  • Humans
  • Hyperammonemia / microbiology*
  • Hyperammonemia / therapy
  • Hypoxia-Ischemia, Brain / microbiology
  • Infant
  • Infant, Newborn
  • Male
  • Sepsis / complications*
  • Sepsis / therapy

Substances

  • Ammonia