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Pediatr Dermatol. 2001 Mar-Apr;18(2):123-6.

Lichenoid eruption following hepatitis B vaccination: first North American case report.

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Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.


Lichen planus is often found in association with a variety of underlying conditions. In particular, liver diseases such as primary biliary cirrhosis, primary sclerosing cholangitis, hepatitis C, and hepatitis B have been implicated in cutaneous lichen planus. Of interest, there is mounting evidence that lichen planus-like eruptions can occur following administration of the hepatitis B vaccine, which has recently become a routine immunization in many parts of the world. We present what we believe to be the first North American case of lichenoid drug eruption associated with the hepatitis B vaccine and provide a brief review of other reported cases of lichenoid eruption seen following hepatitis B vaccination.

[Indexed for MEDLINE]

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