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Oral Dis. 2001 Mar;7(2):123-30.

Cherubism--clinical picture and treatment.

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1
Clinic of Maxillofacial Surgery, Institute of Dentistry, Medical University of Lodz, Kopcinskiego 22 PL-90153 Lodz, Poland.

Abstract

Cherubism is a rare, painless, disfigurating disease primarily affecting bones of the jaws.

OBJECTIVE:

To report on five patients with cherubism. The symptoms of the disease, methods of management and possible mode of inheritance are discussed and literature is reviewed.

PATIENTS:

The study involves five cherubs, members of one family. The diagnoses were based on history, physical examination, laboratory tests, X-ray parameters, and clinical follow-up. One member of the family had surgical intervention. The remaining cases were left for observation.

RESULTS:

Good aesthetic and long lasting effect was reached in the operated patient.

CONCLUSIONS:

Treatment is unnecessary unless functional or emotional disturbances develop. An autosomal recessive pattern of inheritance is suggested for these cases, although autosomal dominant transmission has been previously established.

PMID:
11355438
[Indexed for MEDLINE]
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