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J Gastroenterol Hepatol. 2001 Apr;16(4):481-3.

Ranitidine-related Stevens-Johnson syndrome in patients with severe liver diseases: a report of two cases.

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Department of Medicine, Taipei Veterans General Hospital, Taiwan, Republic of China.


Ranitidine is widely used and well tolerated. Ranitidine-related skin eruption is rare and usually mild. We presented two patients who developed Stevens-Johnson syndrome after ranitidine therapy. Before therapy, both patients had severe liver disease and jaundice. The first was a case of ketoconazole-induced hepatitis, and the second was a case of hepatitis C-related liver cirrhosis with hepatocellular carcinoma. Ranitidine was the most likely drug responsible for causing Stevens-Johnson syndrome in these two patients.

[Indexed for MEDLINE]

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