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Curr Opin Cell Biol. 2001 Jun;13(3):274-80.

Mediator complexes and transcription.

Author information

1
Cell Biology Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

Abstract

Over the past decade, various components of the transcription machinery have been identified as potential targets for activators. Recently, metazoan versions of yeast Mediator have been isolated and found to act as key coactivators to many transcription factors. Recent work has defined the composition, function and biology of metazoan mediator complexes, which has led us to propose a new nomenclature for the variously named versions of the mediator complex.

PMID:
11343897
DOI:
10.1016/s0955-0674(00)00209-x
[Indexed for MEDLINE]

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