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Leuk Lymphoma. 2001 Mar;41(1-2):217-20.

Idiopathic thrombocytopenic purpura following successful treatment of acute lymphoblastic leukemia.

Author information

1
Department of Leukemia at the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Abstract

Thrombocytopenia is common in patients with acute lymphocytic leukemia (ALL) at diagnosis. It is a universal side effect of dose-intensive regimens employed in the treatment of adult ALL. In patients with ALL who achieve remission, thrombocytopenia frequently indicates relapse. We report three adult patients successfully treated for ALL who developed thrombocytopenia and were found to have immune-mediated thrombocytopenia (ITP). Possible pathophysiologic mechanisms underlying the association of ALL and ITP are discussed.

PMID:
11342378
DOI:
10.3109/10428190109057975
[Indexed for MEDLINE]

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