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Eur J Gastroenterol Hepatol. 2001 Apr;13(4):425-7.

Eosinophilic gastroenteritis treated with non-enteric-coated budesonide tablets.

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Department of Gastroenterology and Hepatology, University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.


A patient who presented with upper abdominal pain, nausea and ascites together with peripheral eosinophilia is described. Based on a surgical full-thickness biopsy of the antrum, the diagnosis of eosinophilic gastroenteritis was made. Treatment with prednisone resulted in a clinical response, but the prednisone dose could not be lowered below 5 mg. We preferred to treat the patient with corticosteroids with minimal systemic side effects. As there was gastric involvement, we could not give enteric-coated budesonide capsules. Therefore, we treated the patient with budesonide tablets, which were designed originally for use as a clysma but now are given orally. With this treatment regimen, the patient has been in remission for more than 2 years.

[Indexed for MEDLINE]

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