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Exerc Sport Sci Rev. 2001 Apr;29(2):82-7.

Excitation-contraction uncoupling: major role in contraction-induced muscle injury.

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Department of Physical Therapy, Georgia State University, Atlanta, Georgia, USA.


The mechanisms that account for the strength loss after contraction-induced muscle injury remain controversial. We present data showing that (1) most of the early strength loss results from a failure of excitation-contraction coupling and (2) a slow loss of contractile protein in the days after injury prolongs the recovery time.

[Indexed for MEDLINE]

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