Send to

Choose Destination
Trends Plant Sci. 2001 May;6(5):206-11.

Vacuolar H(+) pyrophosphatases: from the evolutionary backwaters into the mainstream.

Author information

Plant Science Institute, Dept Biology, University of Pennsylvania, 19104-6018, USA.


Vacuolar-type H(+)-translocating inorganic pyrophosphatases have long been considered to be restricted to plants and to a few species of phototrophic bacteria. However, in recent investigations, these pyrophosphatases have been found in organisms as disparate as thermophilic Archaea and parasitic protists, and have resulted in the definition of a novel subclass in plants themselves. Among the many evolutionary and practical implications of these findings is the possibility that this research will spawn new approaches to the treatment of several prolific and debilitating parasite-mediated infections.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center