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Nat Rev Mol Cell Biol. 2001 May;2(5):392-6.

Cell control by membrane-cytoskeleton adhesion.

Author information

1
Department of Biological Sciences, PO Box 2408, Columbia University, Sherman Fairchild Center, 1212 Amsterdam Avenue, New York, NY 10027, USA. ms2001@columbia.edu

Abstract

The rates of mechanochemical processes, such as endocytosis, membrane extension and membrane resealing after cell wounding, are known to be controlled biochemically, through interaction with regulatory proteins. Here, I propose that these rates are also controlled physically, through an apparently continuous adhesion between plasma membrane lipids and cytoskeletal proteins.

PMID:
11331914
DOI:
10.1038/35073095
[Indexed for MEDLINE]

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