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J Androl. 2001 May-Jun;22(3):358-9.

Interpreting positive studies.

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Office of Medical Research, Children's Mercy Hospital, Kansas City, Missouri 64108, USA.


When examining the results of a positive research study, one needs to consider two issues of clinical relevance. First, is the outcome measure of direct interest to patients, or is it clearly linked to a measure of direct interest to patients? Second, is the difference large enough to lie outside the range of clinical indifference? Don't accept the findings of a positive research study without a careful consideration of clinical relevance.

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