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J Clin Microbiol. 2001 May;39(5):1972-4.

Comparison of sequence analysis and the INNO-LiPA HBV DR line probe assay for detection of lamivudine-resistant hepatitis B virus strains in patients under various clinical conditions.

Author information

1
Institute of Virology, University of Vienna, Kinderspitalgasse 15, A-1095 Vienna, Austria. stephan.aberle@univie.ac.at

Abstract

A line probe assay (INNO-LiPA HBV DR) detecting drug-resistant hepatitis B virus (HBV) strains was evaluated. Results concordant with sequence analysis were obtained with 48 of 56 serum samples from HBV-infected patients undergoing lamivudine therapy. In eight cases, additional minor subpopulations could be identified by the line probe assay.

PMID:
11326026
PMCID:
PMC88061
DOI:
10.1128/JCM.39.5.1972-1974.2001
[Indexed for MEDLINE]
Free PMC Article

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