Send to

Choose Destination
See comment in PubMed Commons below
Carbohydr Res. 2001 Mar 22;331(2):119-27.

Synthesis of biotinylated bis(D-glucose) derivatives for glucose transporter photoaffinity labelling.

Author information

Department of Biology and Biochemistry, University of Bath, Claverton Down, UK.


New diazirine based bis-glucose derivatives for tagging glucose transporters have been synthesised. These included two biotinylated compounds linked either by an aminocaproate or by a cleavable dithiol link. These compounds have been derivatised via a key skeleton compound that can be easily used for introduction of additional tags. Studies on the erythrocyte glucose transporter (GLUT1) and the insulin-stimulated adipose cell transporter (GLUT4) have revealed the biotinylated photoreactive bis-glucose compounds are effective labelling reagents.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center