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Eur J Hum Genet. 2001 Mar;9(3):153-9.

Brain studies of mouse models for neurogenetic disorders using in vivo magnetic resonance imaging (MRI).

Author information

1
Department of Medical Genetics, University of Antwerp, Antwerp, Belgium. fkooy@uia.ac.be

Abstract

Magnetic resonance imaging (MRI) is a technique commonly used to detect neural abnormalities in routine clinical practice. It is perhaps less well known that the technique can be adapted to measure various anatomical and physiological features of small laboratory rodents. This review focuses on the potential of the MRI technique to image the brain of (transgenic) mouse models for neurological diseases, and aims to introduce these exciting new technological developments to the non-specialist reader.

PMID:
11313752
DOI:
10.1038/sj.ejhg.5200606
[Indexed for MEDLINE]
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