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Eur Neuropsychopharmacol. 2001 Apr;11(2):181-2.

Effect of amantadine on weight gain during olanzapine treatment.

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1
Department of Psychiatry, Hôpital Notre-Dame, Avenue Delmée 9, B-7500, Tournai, Belgium.

Abstract

Patients treated with olanzapine may gain weight, especially in the first months of therapy. Amantadine (100-300 mg/day) was started in 12 patients having a mean weight gain of 7.3 kg during olanzapine treatment. The patients' weight stabilised and over 3-6 months they lost an average of 3.5 kg. No clinical deterioration occurred and no adverse effects were reported. These observations merit confirmation in randomised, controlled trials.

PMID:
11313165
[Indexed for MEDLINE]
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