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Emerg Infect Dis. 2001 Mar-Apr;7(2):188-92.

Controlling antimicrobial resistance in hospitals: infection control and use of antibiotics.

Author information

  • 1Cook County Hospital and Rush Medical College, Chicago, Illinois 60612, USA. rweinste@rush.edu

Abstract

Antimicrobial-drug resistance in hospitals is driven by failures of hospital hygiene, selective pressures created by overuse of antibiotics, and mobile genetic elements that can encode bacterial resistance mechanisms. Attention to hand hygiene is constrained by the time it takes to wash hands and by the adverse effects of repeated handwashing on the skin. Alcohol-based hand rubs can overcome the time problem and actually improve skin condition. Universal glove use could close gaps left by incomplete adherence to hand hygiene. Various interventions have been described to improve antibiotic use. The most effective have been programs restricting use of antibiotics and computer-based order forms for health providers.

PMID:
11294703
PMCID:
PMC2631704
DOI:
10.3201/eid0702.700188
[PubMed - indexed for MEDLINE]
Free PMC Article
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