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Bioorg Med Chem Lett. 2001 Apr 9;11(7):909-13.

LY294002-geldanamycin heterodimers as selective inhibitors of the PI3K and PI3K-related family.

Author information

1
Department of Molecular Oncogenesis, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. chiosisg@mskmail.mskcc.org

Abstract

Several LY294002-GM heterodimers were synthesized with the intent of modulating their activity in the presence of hsp90 and thereby creating selective inhibitors of PI3K and PI3K-related family.

PMID:
11294389
DOI:
10.1016/s0960-894x(01)00099-3
[Indexed for MEDLINE]

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