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Infect Immun. 2001 May;69(5):3516-8.

YopB of Yersinia enterocolitica is essential for YopE translocation.

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1
Department of Cell and Molecular Biology, Umeå University, 901 87 Umeå, Sweden.

Abstract

A previous study has shown that YopB of Yersinia spp. is essential for translocation of Yop effectors across the eucaryotic plasma membrane (M.-P. Sory and G. R. Cornelis, Mol. Microbiol. 14:583--594, 1994). However, this role was recently challenged (V. T. Lee and O. Schneewind, Mol. Microbiol. 31:1619--1629, 1999). Using protease protection and digitonin extraction, we reconfirm that YopB of Yersinia enterocolitica is essential for the translocation of YopE into HeLa cell monolayers.

PMID:
11292787
PMCID:
PMC98323
DOI:
10.1128/IAI.69.5.3516-3518.2001
[Indexed for MEDLINE]
Free PMC Article
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