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Trends Parasitol. 2001 Mar;17(3):150-3.

In vitro cultivation and characterization of axenic amastigotes of Leishmania.

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1
Division of Biochemistry, Central Drug Research Institute, -226001, Lucknow, India

Abstract

The establishment of axenic cultures of the amastigote stage of Leishmania is important to understand the mechanisms regulating the differentiation, survival and pathogenicity of the parasite with a view to develop and identify molecular and chemotherapeutic targets. Recent developments in axenic culture and the characterization of amastigotes of different species of Leishmania are discussed.

PMID:
11286801
[Indexed for MEDLINE]
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