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Trends Parasitol. 2001 Mar;17(3):122-6.

Possible modes of action of the artemisinin-type compounds.

Author information

1
UNDP/World Bank/WHO Special Programme on Research and Training in Tropical Diseases, CDS Cluster, 20, avenue Appia, CH-1211, Geneva, Switzerland. olliarop@who.ch

Erratum in

  • Trends Parasitol 2001 Jun;17(6):268.

Abstract

Artemisinin-type compounds are used for the treatment of uncomplicated and severe forms of malaria. They reduce parasitaemia more rapidly than any other antimalarial compound known, and are effective against multidrug-resistant parasites. However, uncertainties remain as to how they act on the parasite and cause toxicity. In this review, we summarize current ideas.

PMID:
11286794
[Indexed for MEDLINE]

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