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Arch Microbiol. 2001 Feb;175(2):79-85.

The clc element of Pseudomonas sp. strain B13 and other mobile degradative elements employing phage-like integrases.

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Swiss Federal Institute for Environmental Science and Technology (EAWAG), Ueberlandstrasse 133, Postfach 611, CH 8600, Dübendorf, Switzerland.


Genes for metabolic pathways in bacteria that degrade aromatic or aliphatic pollutants have mostly been confined to either plasmid DNAs or to the chromosome. For a few pathways, including classical pathways for chlorocatechol and biphenyl degradation, recent evidence has been obtained for location of the pathway genes on mobile DNA elements which employ phage-like integrases. This enables the DNA elements to integrate into specific sites on the chromosome and yet to excise and transfer to other host bacteria. This mini-review gives an overview of those elements and their relationship to an increasing number of phage-like elements associated with bacterial virulence.

[Indexed for MEDLINE]

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