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Nat Rev Mol Cell Biol. 2001 Apr;2(4):247-56.

mRNA localization: message on the move.

Author information

1
Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Im Neuenheimer Feld 282, D-69120 Heidelberg, Germany. r.jansen@mail.zmbh.uni-heidelberg.de

Abstract

Cytoplasmic messenger RNA localization is a key post-transcriptional mechanism of establishing spatially restricted protein synthesis. The characterization of cis-acting signals within localized mRNAs, and the identification of trans-acting factors that recognize these signals, has opened avenues towards identifying the machinery and mechanisms involved in mRNA transport and localization.

PMID:
11283722
DOI:
10.1038/35067016
[Indexed for MEDLINE]

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