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Int J Antimicrob Agents. 2001 Mar;17(3):229-31.

In vitro activity of four fluoroquinolones against Mycobacterium tuberculosis.

Author information

  • 1Section of Microbiology, Hospital General Universitario de Elche, Universidad Miguel Hernández, 03202 Elche Alicante, Spain. jcrd@retemail.es

Abstract

The in vitro activity of ciprofloxacin, ofloxacin, levofloxacin and moxifloxacin against strains of Mycobacterium tuberculosis was studied. Moxifloxacin and levofloxacin showed the greatest activity having an MIC(90) of 1 mg/l. The MIC(90) for ofloxacin was 2 mg/l and for ciprofloxacin 4 mg/l. Further studies should be made to determine the role played by these compounds in the treatment of tuberculosis.

PMID:
11282270
[PubMed - indexed for MEDLINE]
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