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Genet Res. 2001 Feb;77(1):61-6.

Linkage disequilibrium mapping of the bolting gene in sea beet using AFLP markers.

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1
Novartis Seeds AB, PO Box 302, S-261 23 Landskrona, Sweden. mats.hansen@syngenta.com

Abstract

The possibility of using linkage disequilibrium mapping in natural plant populations was assessed. In studying linkage disequilibrium among 137 mapped AFLP markers in four populations of sea beet (Beta vulgaris ssp. maritima (L.) Arcang.) it was shown that tightly linked loci could be detected by screening for associations. It was hypothesized that the short distances spanned by linkage disequilibrium enable markers that are very tightly linked to a target gene to be identified. The hypothesis was tested by whole-genome screening of AFLP markers for association with the gene for the annual growth habit, the B gene, in a sample of 106 sea beets. Despite the dominant nature of AFLP, two markers showing significant linkage disequilibrium with the B gene were detected. The results indicate the potential use of linkage disequilibrium for gene mapping in natural plant populations.

PMID:
11279831
[Indexed for MEDLINE]
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