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Nat Genet. 2001 Apr;27(4):372-3.

Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci.

Author information

1
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. william.cookson@ndm.ox.ac.uk

Abstract

We have carried out a genome screen for atopic dermatitis (AD) and have identified linkage to AD on chromosomes 1q21, 17q25 and 20p. These regions correspond closely with known psoriasis loci, as does a previously identified AD locus on chromosome 3q21. The results indicate that AD is influenced by genes with general effects on dermal inflammation and immunity.

PMID:
11279517
DOI:
10.1038/86867
[Indexed for MEDLINE]
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