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Bioorg Med Chem Lett. 2001 Mar 26;11(6):793-5.

A novel fluorinated tryptamine with highly potent serotonin 5-HT1A receptor agonist properties.

Author information

1
Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, IN 47907-1333, USA.

Abstract

Synthesis and biological evaluation of a novel fluorinated tryptamine analogue are described. This new compound 1-(4-fluoro-5-methoxyindol-3-yl)pyrrolidine (2) was found to be a potent serotonin 5-HT1A agonist.

PMID:
11277522
DOI:
10.1016/s0960-894x(01)00062-2
[Indexed for MEDLINE]

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