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Genome Biol. 2001;2(3):REVIEWS0002. Epub 2001 Mar 9.

Nuclear dynamics: where genes are and how they got there.

Author information

1
Division of Gene Regulation and Expression, Wellcome Trust Biocentre, University of Dundee, Dow Street, Dundee, DD1 5EH, UK. j.swedlow@dundee.ac.uk

Abstract

DNA is highly organized spatially, both within domains of chromatin along each chromosome and within the nucleus as a whole. Recent studies suggest that chromatin localization can affect transcriptional and replicational activity. The similarity between the movements of chromatin nuclear bodies suggests a common mechanism that regulates nuclear dynamics.

PMID:
11276427
PMCID:
PMC138913
DOI:
10.1186/gb-2001-2-3-reviews0002
[Indexed for MEDLINE]
Free PMC Article

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