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Nat Neurosci. 2001 Apr;4(4):391-5.

Morphological correlates of functionally defined synaptic vesicle populations.

Author information

1
Howard Hughes Medical Institute and Molecular Neurobiology Lab, The Salk Institute, 10010 N. Torrey Pines Road, La Jolla, California 92037, USA.

Abstract

By combining photoconversion of FM1-43-stained vesicles and electron microscopy of hippocampal synapses, we find evidence that the population of morphologically docked synaptic vesicles corresponds to the release-ready neurotransmitter quanta. Furthermore, those synaptic vesicles that are participating in cycles of exo- and endocytosis tend to be closer to the active zone than vesicles that are being held in reserve.

PMID:
11276229
DOI:
10.1038/86042
[Indexed for MEDLINE]

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