Recurrent pleomorphic adenoma: uninodular versus multinodular disease

Ir J Med Sci. 2000 Jul-Sep;169(3):201-3. doi: 10.1007/BF03167696.

Abstract

Background: While treatment of previously untreated pleomorphic adenoma is relatively straightforward, recurrent pleomorphic adenoma presents a management problem with increased risk of injury to the facial nerve and an increased risk of malignant transformation in recurrent disease.

Aims: The objectives of this study were to review the management of recurrent pleomorphic adenoma in our unit to identify factors that might help treatment of future cases.

Methods: We reviewed the management of pleomorphic adenoma at our department over an eight-year period from 1990-1998 and present our experience of recurrent pleomorphic adenoma of the parotid gland and parapharyngeal space.

Results: Twelve patients were treated with recurrent pleomorphic adenoma. In 10 of these, the site of recurrence was in the parotid gland with the remainder occurring in the parapharyngeal space. Type of recurrence was uninodular or multinodular, the former being easier to treat. Three patients required adjuvant radiotherapy. None of our patients had permanent facial nerve damage.

Conclusions: In order to prevent recurrence of pleomorphic adenoma of the parotid gland, we recommend formal superficial parotidectomy for first time surgery.

Publication types

  • Comparative Study

MeSH terms

  • Adenoma, Pleomorphic / pathology
  • Adenoma, Pleomorphic / surgery*
  • Adult
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local*
  • Parotid Gland / surgery*
  • Parotid Neoplasms / pathology
  • Parotid Neoplasms / surgery*