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IMA J Math Appl Med Biol. 2000 Dec;17(4):395-413.

Lotka-Volterra equations with chemotaxis: walls, barriers and travelling waves.

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Centre in Statistical Science and Industrial Mathematics, School of Mathematical Sciences, Queensland University of Technology, Brisbane, Australia.


In this paper we consider a simple two species model for the growth of new blood vessels. The model is based upon the Lotka-Volterra system of predator and prey interaction, where we identify newly developed capillary tips as the predator species and a chemoattractant which directs their motion as the prey. We extend the Lotka-Volterra system to include a one-dimensional spatial dependence, by allowing the predators to migrate in a manner modelled on the phenomenon of chemotaxis. A feature of this model is its potential to support travelling wave solutions. We emphasize that in order to determine the existence of such travelling waves it is essential that the global relationships of a number of phase plane features other than the equilibria be investigated.

[Indexed for MEDLINE]

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