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Curr Biol. 2001 Mar 6;11(5):R178-81.

Cell cycle: Flies teach an old dogma new tricks.

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1
Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

Abstract

E2F transcription factors are thought to influence the G1-S cell-cycle transition by controlling expression of genes required for growth and DNA synthesis. But emerging evidence suggests E2F complexes can control the cell cycle independently of transcription by directly regulating DNA replication origin usage during S phase.

PMID:
11267887
[Indexed for MEDLINE]
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