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Biochim Biophys Acta. 2001 Mar 19;1518(1-2):168-72.

Isolation and characterization of cDNAs for the protein kinase HIPK2.

Author information

1
Universit├Ąts-Kinderklinik Ulm, Forschungslabore, Prittwitzstrasse 43, D-89175 Ulm, Germany.

Abstract

HIPK2 (homeodomain-interacting protein kinase 2) is a CD95 binding partner in yeast. Its primary amino acid sequence is highly conserved between human and mouse. The highest HIPK2 mRNA expression is found in neuronal tissue. The HIPK2 gene is located on human chromosome 7q33-35 and the protein is mainly localized in the nucleus. HIPK2 has been described to play a role as a co-repressor for homeodomain transcription factors.

PMID:
11267674
DOI:
10.1016/s0167-4781(00)00308-0
[Indexed for MEDLINE]

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