Aromatic regions of ^{1}H-^{1}H NOESY spectra. Spectra are shown for Ca^{2+}-saturated N-camY (*A*) and Ca^{2+}-saturated Q41L-K75I (*B*). As expected from the open-state structure of N-cam, several cross-peaks between Tyr19 and other aromatics are observed (dashed box). These cross-peaks are not expected for the closed form. Assignments—based on COSY, TOCSY, and NOESY correlations, similarities with published assignments (, ; ), and consistency with the know structures—are as follows. For (*A*) Y19, Y19 (Hɛ, 6.77) to (Hδ, 7.14); Y78, Y78 (Hɛ, 6.74) to (Hδ, 7.05); a, F16 (Hɛ, 6.96) to (Hζ, 7.11); b, F68 (Hɛ, 6.84) to Y19 (Hδ, 7.14); c, F68 (Hɛ, 6.84) to (Hζ, 6.97); d, Y19 (Hɛ, 6.77) to F68 (Hζ, 6.97); e, F16 (Hδ, 6.55) to (Hζ, 7.11); f, F16 (Hδ, 6.55) to (Hɛ, 6.96); g, F16 (Hδ, 6.55) to F68 (Hɛ, 6.84); h, Y19 (Hɛ, 6.77) to F65* j, F65* (H*, 6.69) to F65* (Hɛ, 7.15). For (*B*) Y19, Y19 (Hɛ, 6.76) to (Hδ, 7.13); Y78, Y78 (Hɛ, 6.72) to (Hδ, 7.02); a, F16 (Hɛ, 6.92) to (Hζ, 7.21); c, F68 (H*, 6.93) to (H*, 7.21); e, F16 (Hδ, 6.48) to (Hζ, 7.21); f, F16 (Hδ, 6.48) to (Hɛ, 6.92); i, Y19 (Hɛ, 6.76) to (*); j, F65* (H*, 6.68) to F65* (Hɛ, 7.15). *Not determined or uncertainty in the assignment.

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