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Nat Rev Neurosci. 2000 Dec;1(3):191-8.

Neural consequences of environmental enrichment.

Author information

1
Salk Institute for Biological Studies, La Jolla, California 92037, USA. gage@salk.edu

Abstract

Neuronal plasticity is a central theme of modern neurobiology, from cellular and molecular mechanisms of synapse formation in Drosophila to behavioural recovery from strokes in elderly humans. Although the methods used to measure plastic responses differ, the stimuli required to elicit plasticity are thought to be activity-dependent. In this article, we focus on the neuronal changes that occur in response to complex stimulation by an enriched environment. We emphasize the behavioural and neurobiological consequences of specific elements of enrichment, especially exercise and learning.

PMID:
11257907
DOI:
10.1038/35044558
[Indexed for MEDLINE]

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