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Nat Rev Neurosci. 2001 Mar;2(3):205-9. doi: 10.1038/35058582.

Eph receptors and neural plasticity.

Author information

1
Neuroscience Department, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana 46285, USA. gerlai_robert@lilly.com

Abstract

Eph receptor tyrosine kinases are largely known for their involvement in brain development but, as some of these receptor tyrosine kinases are also expressed in adults, their possible role in the mature nervous system has begun to be explored. Evidence for the involvement of Eph receptors in synaptic plasticity, learning and memory is only emerging and needs corroboration. However, it is likely that the actions of Eph kinases in the adult brain will attract significant attention and become a fertile research area, as occurred in the case of the neurotrophins.

PMID:
11256081
DOI:
10.1038/35058582
[Indexed for MEDLINE]
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