Send to

Choose Destination
See comment in PubMed Commons below
Biochimie. 2001 Jan;83(1):117-20.

Conserved sequence motif at the C-terminus of the bacterial cell-division protein FtsA.

Author information

  • 1MRC Laboratory of Molecular Biology, Hills Road, CB2 2QH, Cambridge, UK.


FtsA is an essential part of the septal ring structure in bacterial cell division. Two peptide-protein interactions are known in this process: FtsA and ZipA bind the C-terminus of FtsZ, the bacterial tubulin homologue, which is the first septal component to appear at the septum. Our recent crystal structure of FtsA revealed a possible peptide binding site on FtsA and a long disordered C-terminal region. Here we show that all FtsA proteins contain a conserved 10-13 residue motif at the C-terminal end that may facilitate targeting of downstream septal components.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center