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Nat Rev Genet. 2000 Nov;1(2):134-44.

Mobile elements and the human genome.

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1
Department of Genetics, 475 Clinical Research Building, 415 Curie Boulevard, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

Erratum in

  • Nat Rev Genet 2001 Jan;2(1):78.

Abstract

Genomic DNA is often thought of as the stable template of heredity, largely dormant and unchanging, apart from perhaps the occasional point mutation. But it has become increasingly clear that DNA is dynamic rather than static, being subjected to rearrangements, insertions and deletions. Much of this plasticity can be attributed to transposable elements and their genomic relatives.

PMID:
11253653
DOI:
10.1038/35038572
[Indexed for MEDLINE]
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