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Nat Rev Mol Cell Biol. 2000 Nov;1(2):91-100.

Cadherins in embryonic and neural morphogenesis.

Author information

1
Department of Zoology, University of Toronto, 25 Harbord Street, Toronto, Ontario M5S 3G5, Canada. utepass@zoo.utoronto.ca

Abstract

Cadherins not only maintain the structural integrity of cells and tissues but also control a wide array of cellular behaviours. They are instrumental for cell and tissue polarization, and they regulate cell movements such as cell sorting, cell migration and cell rearrangements. Cadherins may also contribute to neurite outgrowth and pathfinding, and to synaptic specificity and modulation in the central nervous system.

PMID:
11253370
DOI:
10.1038/35040042
[Indexed for MEDLINE]
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