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Nat Rev Mol Cell Biol. 2000 Nov;1(2):110-9.

Secrets of actin-based motility revealed by a bacterial pathogen.

Author information

1
Department of Biochemistry, Stanford University School of Medicine, 279 Campus Drive West, Stanford, California 94305-5307, USA.

Abstract

Actin-based cell motility is a complex process involving a dynamic, self-organizing cellular system. Experimental problems initially limited our understanding of this type of motility, but the use of a model system derived from a bacterial pathogen has led to a breakthrough. Now, all the molecular components necessary for dynamic actin self-organization and motility have been identified, setting the stage for future mechanistic studies.

PMID:
11253363
DOI:
10.1038/35040061
[Indexed for MEDLINE]
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