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Nat Rev Genet. 2001 Jan;2(1):33-8.

Ancient origin of the Hox gene cluster.

Author information

1
School of Animal & Microbial Sciences, University of Reading, Whiteknights, Reading RG6 6AJ, UK. d.e.k.ferrier@reading.ac.uk

Abstract

The Hox gene cluster has a crucial function in body patterning during animal development. How and when this gene cluster originated is being clarified by recent data from Cnidaria, a basal animal phylum. The characterization of Hox-like genes from Hydra, sea anemones and jellyfish has revealed that a Hox gene cluster is extremely ancient, having originated even before the divergence of these basal animals.

PMID:
11253066
DOI:
10.1038/35047605
[Indexed for MEDLINE]

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